Other than the mRNA inoculations themselves, rarely has a Big Pharma concoction failed as spectacularly as Paxlovid. It simply doesn't do a damn thing.
The New England Journal of Medicine has yet another study showing that Paxlovid has no impact on patients under 65.
No evidence of benefit was found in younger adults.
Even the corporate media is unwilling to expend any credibility on behalf of the drug.
Bottom line: keep taking your vitamins. They're still your best bet.
Didn't seem to have any impact on Obiden and FauxQi, either. ("...no impact on patients under 65.")
This one interests me, as the original HR pax trial did show benefit in younger age groups, 1,817 of 2,085 participants were under 65.
This new one mostly seems like poor study design. "Eligibility" was determined by scoring - you were eligible if you had enough co-factors (the required score isn't given) - but it clearly looks like in practice only highest scorers were prescribed Pax. The skew in comorbidities in Table 1 is extreme. So the treatment group was way more at-risk than the "control." But is the skew the same in both age groups? I see no way to figure this out. The authors need a slap on the head for not tailoring their analysis to the data set.
Better redemption is in supplemental tables S4 and S5 https://www.nejm.org/doi/suppl/10.1056/NEJMoa2204919/suppl_file/nejmoa2204919_appendix.pdf. Paxlovid reduces risk in 40-64 "without prior immunity." So this replicates the HR trial. It increases risk in those "with prior immunity." This may be because "prior immunity" reduces eligibility score and thus raises the bar for comorbidities needed to actually be prescribed (thus raising the comorbidities in the "prior immunity" treatment group).
"Prior immunity" seems probably under-recorded in both groups though it might be a reflection of disproportionately high Arab community patients covered in this health system (52% of total Israel pop.).
Well Peter, at $530 a course of treatment it does do something, it makes them a bunch of cash.
Got this off one of the info sites.
See that first pharmacy listed, with 6,482 "courses" of treatment available?
That is $3,435,460 right there! One fucking pharmacy!
And every pharmacy on the list has over one half million dollars worth on hand!
Pharmacy with the most courses of Paxlovid available (Updated July 2022):
Provider name Location Paxlovid courses available
CIMPAR OAK PARK 101 MADISON ST STE 300, Cook IL 6,482
Walmart Pharmacy #1623 2150 Wilkes Barre Twp Mkt Pl, Luzerne PA 5,998
DPH Central Pharmacy 241 N. Figueroa St., Room B-9, Los Angeles CA 3,670
Walmart Pharmacy #5737 3475 BLACK FOREST DR, Washington AR 3,302
ALTO PHARMACY 100 PARK AVE, New York NY 2,994
BLESSING HOSPITAL 1005 Broadway @ 11th St, Adams IL 2,938
Polaris Pharmacy Services PRX1 2900 NW 60th Street, Broward FL 2,760
COMMUNITY REGIONAL MEDICAL CENTER 2823 Fresno Street, Fresno CA 2,580
CEDARFIELD PHARMACY 7016 LEE PARK RD, Hanover VA 1,980
SHOP RITE PHCY 554 201 Dalton Drive, Gloucester NJ 1,930
HEMMANUEL PHARMACY LLC 3914 N JACKSON RD, Hidalgo TX 1,920
CHUUK STATE HOSPITAL 1 WENO, Federated States of Micronesia FM 1,882
DB PHARMACY 12100 VETERANS MEMORIAL DR, STE#E, Harris TX 1,740
COACHELLA VALLEY PHARMACY 77932 COUNTRY CLUB STE 22, Riverside CA 1,622
Midway T2T 1400 University Ave W, Ramsey MN 1,609
LBJ TROPICAL MEDICAL CENTER FAGAALU VILLAGE, American Samoa AS 1,608
PHYSICIANS PLAZA PHARMACY 5000 Physicians Blvd, Kern CA 1,516
DESERT OASIS HEALTHCARE MEDICAL GRO 275 N EL CIELO RD, Riverside CA 1,516
CLEVELAND CLINIC FOUNDATION - MAIN 9500 EUCLID AVE, Cuyahoga OH 1,416
SHOP RITE PHCY 603 4 W ROOSEVELT BLVD, Cape May NJ 1,410
NORTH SHORE UNIV HOSP 225 Community Dr. Suite 140, Nassau NY 1,392
YNHH/MAIN HOSPITAL 55 Park Street, New Haven CT 1,360
KAISER PERM SUPPLY MAIN 2921 Naches Ave SW, King WA 1,323
M HEALTH FAIRVIEW CLINICS 711 Kasota Ave SE, Hennepin MN 1,220
MEMORIALCARE LONG BEACH MEDICAL CEN 2801 Atlantic Av, Los Angeles CA 1,120
PHOEBE PUTNEY MEMORIAL HOSPITAL 417 W. Third Avenue, Dougherty GA 1,100
North Sunflower Med Center Pharmacy 840 N. Oak Ave., Sunflower MS 1,080
CarolinaCARE 4400 Golf Acres Dr, Mecklenburg NC 1,080
OSU - OSU WEXNER MEDICAL CTR 410 W 10TH AVENUE 327 RHODES HALL, Franklin OH 1,065
FROEDTERT PHARMACY 050 9200 W. WISCONSIN AVE, Milwaukee WI 1,019
NL EASTERN MAINE MEDICAL CENTER 489 State st, Penobscot ME 1,012