Keep in mind that the vaccines were never actually intended for monkeypox. It's just characteristic of the relative closeness of orthopoxviruses that a smallpox vaccine has an efficacy profile against monkeypox.
And neither ACAM2000 nor Jynneos are routinely administered even in Africa. So even prior to this current outbreak there's a who…
Keep in mind that the vaccines were never actually intended for monkeypox. It's just characteristic of the relative closeness of orthopoxviruses that a smallpox vaccine has an efficacy profile against monkeypox.
And neither ACAM2000 nor Jynneos are routinely administered even in Africa. So even prior to this current outbreak there's a whole lot of uncertainty about their actual efficacy against monkeypox.
The 85% efficacy figure is really more of a "best guess" given that the actual target pathogen, smallpox, is no longer endemic anywhere in the world.
Keep in mind that the vaccines were never actually intended for monkeypox. It's just characteristic of the relative closeness of orthopoxviruses that a smallpox vaccine has an efficacy profile against monkeypox.
And neither ACAM2000 nor Jynneos are routinely administered even in Africa. So even prior to this current outbreak there's a whole lot of uncertainty about their actual efficacy against monkeypox.
The 85% efficacy figure is really more of a "best guess" given that the actual target pathogen, smallpox, is no longer endemic anywhere in the world.
Excellent, thank you for explaining